Criminal Invesigations Essay

The purpose of this research paper is to show the role, function, nature and responsibility of the criminal investigator. The Methods Used and the Interpretation of the Collection of Physical Evidence and Understanding of the Sources of Information will be explained within this paper. The Role, Function, Nature and Responsibility of the Criminal Investigator The criminal investigator has specific roles and function within their organization. The duty of a crime scene investigator is to try to assemble and bring together multiple events, information, and interpretations of a crime scene to make it one big picture. Based on physical evidence, testimonies of eyes witnesses, suspects, and the victim he will create scenery to figure out what has happened. He or she is creating a hypothesis in what happen before the crime scene occurred and after. All evidence found in all cases by the investigator has full understanding and knowledge of it in order to be an effective investigator (Physica l Evidence). The mentality of an investigator has to have interest, observative, and have the ability to write down everything that is going on. While on a crime scene he or she will notice what is wrong in the crime scene. For instance, the investigator notices that everything in a home is taken out and thrown on the floor in which the investigator can tell the crime scene is a burglary. In the investigative world, not only each individual investigator learns from each case they take up but from each other. While learning from each other they have to be opened minded and have doubt in order not to interfere with the facts of the case. The job of a criminal investigator has high levels of critical thinking (Police). The Methods Used and the Interpretation of the Collection of Physical Evidence When the investigator is called onto a crime scene they have a lot of work to gather and process. The first initiative officer will turn the crime scene over to them. The investigator might be also in charge of giving out press information based on the crime scene. The first thing that they might observe is the possible of the scene being contaminated by the officers who arrived their initially. The crime scene must be organized, and controlled using the proper methods so that the suspect of the crime scene may be successfully captured (Police).. The investigator will meet with the lead detective and the first responding officer on scene. He or she will interview them the two people on information pertaining to the scene. The investigator will get an understanding on what happened, when it happened, and how the crime occurred. The information received, the investigator will combine his information with theirs and make a logical determination of what happen in the crime scene. The gathered information as if you were a judge to see if the facts and evidence will meet will support the conclusion of the scene (Police). The process of the crime scene investigation is when they receive a call to go to a crime scene. When you arrive at the scene, you will make a list of what is required for this particular crime. Every crime scene is different. As crime scene investigator, you will need to have enough police officers protecting the crime scene and yourself. The officer will have to make sure that no one who is not authorizes to enter the premises stays out. The responding officer or a designated person would be the recorder keeper of authorize personal who enter the crime scene. They would have to write down their name, ID number, date, time, and what department (Police). The crime scene investigator will start to take photographs from the outside. The will take pictures of the entire area. All angles will be necessary from across, behind, on top, and bottom of the crime scene. Pictures will be taken of the street names, numbers, the street itself, vehicles, and street light posts. The more pictures taken; the more evidence you have. Every picture taken should be accounted. A log will be helpful of keeping account of the pictures, what camera, lens and film being used. If video camera is used that is also should be logged into the log sheet. In addition, you may want to write down who had access to photos or video other than the crime scene investigator (Physical Evidence). Now, the crime scene investigator will take note on any damages or any property taken on the outside. All evidence will be taken into photography. Photography will be taken from all angles, close-up and from a distance. Any mark numbers and letters must be place in the one area and be able to fit in one photograph. Next, Diagrams will be made of the crime scene and where the evidence was found. Triangular, rectangular, and baseline diagrams will be made to show a rough measurement of where everything happened. The investigator is always to remember to record location, measurements, and the person who collected the information. The investigator will now move inside the premises of the crime area. The investigator has to make sure he has proper approval and if necessary a search warrant. When entering the premises, you may want to wear protective gear so that you will not contaminate the evidence. Protective gear may include gloves, head and shoe covers, jumpsuit, and a mask. When looking for evidence inside the area, avoid the place where you think the suspect has moved around. The investigator will have less cross contamination on the evidence. Area where the investigator will walk will be around the edges not of the middle of the scenery. They will take notice on the entry point and exit point of the suspect. They will make sure other detectives or investigators in the crime scene to walk in certain paths to not contaminate the crime scene (Police). The crime scene investigator will logically take photographs as he did outside into the interior of the crime scene. They will work either in the same direction or opposite direction in working the crime scene. The crime scene investigator will do the same procedures in all crime scenes. When taking photographs, the investigator will take photographs in a three dimensional way. Photographs will be taken of the floors, walls, and ceilings. Everything must be visible for evidence by taking photos of the four walls. One angle might not be enough to show the evidence needed. Multiple angles must be taken. With all the photos taken, the investigator will make a diagram of the crime scene. It is good to point out the major details of the crime scene such as furniture, entry and exit points, and the victim. Another way of recording evidence is through video camera. Taking video must be only of important video of the crime scene. It may be easier to take video in fifteen second intervals. The investigator will also take video from all angle of the crime scene. After they are done collecting evidence, they will go make another walk through to make sure no missing evidence pertaining to the crime scene. Collaboration with other crime scene investigators and detectives will be done to insure all evidence has been collected. Understanding of the Sources of Information In the line of an investigator, getting enough information is critical. Information can be from physical evidence, the crime scene, interviewing, and interrogations. Interview and interrogations are very different. Interviews are just to gather information of the crime. An interrogation is getting information based on the suspect being involved. An investigator need to know the difference so that the person being interviewed or interrogated will know if they in custody or being asked a few questions. Two key ways of getting information will be witnesses, and interviews (Berg). WitnessesA witness will help out a lot while investigating. When interviewing, there are ten basic steps. The steps are plan ahead, arrange for privacy, identify yourself properly, assemble case facts in advance, have an intentional direction, be timely, avoid interruptions, be a good listener, adjust language level, pace, and demeanor as necessary, and maintain rapport throughout the interview. There are many types of witness which may include willing witnesses, eyewitnesses, reluctant witnesses, silent or disinterested witnesses, unreliable witnesses, frightened witnesses, biased witness, hostile witnesses, timid witnesses and deceitful witnesses. An investigator may also deal with people of many different ages. The investigator will have to identify these witnesses, and if they are children, young adults, or mature adults. They will have different methods on the way they try to receive information and if the information is valid (Berg). Interviews At first, a rapport will be made by the investigator. A rapport is a relationship between the officer and the one being interview knowing theirs empathy. An interview may not exactly occur right after the crime due to the anxiety from the situation. Time is needed before interviewing. It has to be a respectful interview and listening very closely. There two ways to interview a person; cognitive and behavioral analysis. Cognitive interview is reconstructing the circumstances, reporting all information, recalling events in different orders, and changing perspectives. Behavioral analysis is just identifying the person body language to the truth (Berg). Conclusion In conclusion, criminal investigation is a long process of collecting information. They have the most important job. The process of collecting information is extensive. It is critical for them to collect all evidence so that the suspect may be apprehended and justice shall be served when in the court system. Information may be either through physical evidence, interviews, or witnesses (Berg). Works Cited Berg, Bruce L., John J. Horgan, and John J. Horgan. Criminal Investigation. New York, NY: Glencoe/McGraw-Hill, 1998. Print. â€Å"Physical Evidence.† Enotes.com. Enotes.com, n.d. Web. 19 Oct. 2012. . â€Å"Police: Criminal Investigations – Sources Of Information And Evidence In Criminal Investigations.† – Physical, Crime, Polygraph, and Witnesses. N.p., n.d. Web. 19 Oct. 2012. .

Change Agents. Oticon Case

The design of the spaghetti company Is an example of a matrix organizational design, which focused the workers orientations to varying, proved projects In which they approve of. This allowed workers to focus more on the production side, which In the end cut project development time In half. 2. While operating within an industry in which products are complex and technically advanced which would require innovated thinking, Diction a disorganized, free- flowing organizational structure.By doing so, they were able to adapt to changes, which were occurring in the market to better figure out solutions to the problems they would experience. This complex system allowed them to operate more efficiently to better serve their customers. Their strategy was viable as it allowed for quicker lines of communication, increased innovation and a more efficient production process, as in the end their profits eventually doubled from their old strategy. 3.The leadership style at Diction was based on a tas k oriented bureaucratic structure, until they introduced the spaghetti style structure, which turned their strategy into a more employee-oriented style. Kaolin was an example of a discretionary management role as he helped shape the organization in order to change of the company to better suit that to the environmental relationship. The strategy ended up being very successful as it was out of the norm in comparison to other competitors and it also had the full support from the employees of Diction.Although mostly successful, the strategy did fail at their other international factories. This was due to the fact that these factories were accustomed to their own unique traditions In which they refused to let go. Diction should have modified their strategy for these factories to allow them to hold onto their traditions, while at the same time still implementing the overall style they had originally vision. Change Agents. Diction Case By judiciary Diction Case 1 .The spaghetti organizati on is the title given to the transition from a mechanical management structure to a more non-organized style, which allowed for a more style of the company by getting rid of all titles and departments in order to get out of ranks to number 3 in the market. The design of the spaghetti company is an example approved projects in which they approve of. This allowed workers to focus more on the production side, which in the end cut project development time in half. 2. While the fact that these factories were accustomed to their own unique traditions in which

Factors that influence learning Essay

Health Bad health can have a negative impact on a person’s learning. If a person is unwell they are unable to attend school, college or courses. For example, if a person has the flu, they could be unwell for two weeks. In those two weeks they could miss a substantial amount of learning time, leaving them behind with work & unable to move on with their learning at the same pace as their peers. Employment If a person is employed it can have a negative effect on their learning as well as a positive effect. For example; If a 6th form student is studying 4 A-levels and has a part-time job, they will barely have any free time. Resulting in them getting behind with work, not meeting deadlines. This can result in an extreme amount of stress. This is a negative effect on learning. Employment can also have a positive effect on learning, for example, if a person has a job they are going to be learning new skills in the work place. Care responsibilities Read more: Personal factors that affect child development essay If a person has care responsibilities, it can result in a negative effect on a person’s learning. For example; If a student is a young career, and they have to look after a parent, they may be missing a lot of time off school or college to do so, meaning they will be missing out on a lot of work. Also when they are attending school or college they may be worrying about what is happening at home why they aren’t there and if the person they are looking after is ok, this can mean they aren’t concentrating on the work they are supposed to be doing so they could be missing vital pieces of information. Access to a study centre Having or not having access to a study centre can affect a person’s learning. If a person has access to a study centre they will be able to learn more effectively, and complete work, revise and meet deadlines. Meaning they will be have a good learning experience. Although if a person is unable to access a study centre because of circumstances such as low income, they will be unable to learn effectively, complete work, revise or meet deadlines etc†¦ This means that they will fall behind with work and may not be able to achieve the things they would like to. Time Time can be a very huge factor that can influence a person’s learning. For example; if a person doesn’t have much free time they wouldn’t be able to achieve as much as they could if they had enough time to complete work, study and revise. Not having enough time can have a huge negative effect on a person’s learning. Also if a person has a lot of time to study etc†¦ they stand a better chance of achieving greater things, such as a person having a lot of time to revise for their A-level exams stand a better chance of progressing onto university because they are more than likely to achieve better grades than someone who struggles to find time. Specific learning needs If a person has specific learning needs such as dyslexia, and they are unable to access the resources they need such as extra support and coloured overlays, they will find it difficult to learn and may have an un-enjoyable learning experience. This will result in a negative learning experience. Funding for study Funding for study can have huge implications on a person’s learning experience. For example, if a student that is planning to go to university is unable to obtain the funding needed for the course they wish to do, they may be unable to do the course they require for their dream job. Resulting in a negative learning experience. Although if a person is able to get funding for a course at university, they will be able to study the degree they want and will be able to go onto do the job they may have always wanted. However receiving funding could in the long run have a negative effect, because the student maybe worrying about having to pay the grant back. Aspirations Having aspirations can have a positive effect on a person’s learning. This is because they may study harder in hope of achieving their aspirations. For example, a person who wishes to become a doctor later on will concentrate a lot harder than someone who doesn’t know what they want to do later in life,  because the person who aspires to be a doctor will know how hard they have to work to achieve the things needed to pursue such career. Learning styles Learning styles have an impact on a person’s learning experience. For example; If a person is a someone that learns by doing practical tasks and getting hands on, is stuck in a lecture just being dictated they aren’t going to have an enjoyable learning experience and are just going to switch off and not take in any information they are being told because they are bored, resulting in a negative learning experience. Motivation Motivation has an impact on learning experiences. For example; If a student has no motivation to do well, they will more than likely not bother doing any revision or pay attention in class, resulting in bad grades and the inability to move on to higher education or a job because they have been unable to achieve the necessary requirements to do so, resulting in a negative learning experience.

Photographic Portrait Coursework Example | Topics and Well Written Essays - 8000 words

Photographic Portrait - Coursework Example For this he sought a means by which he could generate his work easily through automated image making. Today Photography is a combination of reportage and art. The photographer acts a as manipulator of his subject. He is the creator of his masterpiece unconventional or conventional. It is his knowledge of his equipment his art, his opinion and familiarization of his subject that he can produce and bring forward the unique masterpiece for people to analyze and be mesmerized with. He tells a story through his perspective, his lens. The subject is in the hands of the photographer and it is for him to pull the strings and get the subject do what the photographer wants and produce reactions that the photographer needs. Portrait means painted, drawn, or carved picture of something or a representation of a person especially of face drawn, painted or sculptured. It is also defined as the description or dramatic portrayal of a person. "Portraiture means individualism and as such means diversity, self-expression, and private point of view. The most successful images seem to be those which exist on several planes at once and which reflect the fantasy and understanding of many." Portraiture held different meaning for different times. The oncoming of the twentieth century did away with the carefully poised photographs. The techniques modernized as well as with the subjects the themes as well the photographers. Of the twentieth century the most notable photographers are Annie Leibovitz and Richard Avedon. While Leibovitz style is witty and captures the imagination of the onlookers Avedon's is in contrast captivating with his style of portraying his subjects as edgy. Leibovitz familiarization of her subjects makes them feel easy with her whereas Avedon creates his pictures by making his subjects it in front of the camera and then when they are at ease he shoots. In the 19th century the most popular was miniature portrait which was soon replaced by photography. The first portrait photographers had to compete with the painters so had more of the painter touch to their work. Photography compositions changed in accordance to the period in which they were taken as were themes and subjects. Objective/Aim To study and analyze the theory of photographic portrait and the photographers involved. Learning about the history of photographic portrait and how it evolved during the passage of time. 1- understanding theory of photographic portrait (both historical background and contemporary practices); 2- study portrait work of 2 photographers Avedon and Leibovitz Photographic portraiture: Photographic portraiture has much more to it than just taking a picture and making films. Various tools are incorporated in the process of making a photographic portrait. The goal is always to create something unique. It brings out what is not apparent to the naked eye and instead of capturing the superficial it captures life, personality, mood, relationships etc. A successful photographic portrait is one in which the photographer and the subject both work together in order to obtain perfection. As it aims to bring out the personality hence the subject must be careful about the

Choose an issue surrounding capital punishment (deterrence, innocence, Research Paper

Choose an issue surrounding capital punishment (deterrence, innocence, cost, racial bias, etc.) and use it to argue why or why n - Research Paper Example Many other states in America also released similar reports with respect to the expenses of capital punishment. Billions of Dollars are spent yearly for implementing capital punishment in America. Normal court procedures are impossible in the death penalty cases. The court needs to double confirm that the criminal is eligible for death penalty because of the value associated with human life. â€Å"The essence of American criminal justice system is that â€Å"partisan advocacy of both sides on a case will promote the ultimate objective that the guilty be convicted and the innocent go free† (Ferdic et al, p.37). So, before implementing death penalty, the criminal went through for a series of expensive trial procedures including state and federal supreme courts. The criminal can question the punishment several times in different courts before the final judgment of the Supreme Court. All these court procedures are highly expensive because of the various expensive services (Smart a dvocates, Forensic experts, Investigating officers, witnesses, etc) needed for it.

Dream act Essay Example | Topics and Well Written Essays - 750 words

Dream act - Essay Example Although much of the Dream Act is misunderstood, the fact of the matter is that these children of illegal immigrants must meet stringent requirements and comply with all of the criteria in order to be illegible for the type of amnesty the Act provides. When all the requirements of the Dream Act are met by the candidate, then the minor is given permission to stay in the country for 6 years; upon successful completion of such residence, the individual is then able to apply for citizenship. In this way, the Dream Act allows temporary residency only for minors who have good character. As a function of this, the Dream Act gives an opportunity to build the career of otherwise helpless children who have what many would term a very dark life perennially branded as â€Å"illegal† without the restitution that such an act provides. Due to this reason and many others, I wholeheartedly support this Act. Although one cannot blame certain segments of society for being very anti-illegal immigration (due in no small part to the fact that it is a clear abrogation of the nation’s immigration law), it is however summarily unfair to punish the children of these illegal immigrants with the same labels that condemn their parents to a life on the sidelines of American society. Due to the fact that the children who migrated along with their parents are innocent and helpless, the Act is able to make such a distinction and seek to close a necessary loophole and oversight of current immigration law as to make it more humane and reasonable. However, beyond just being reasonable, the Act allows for an entire generation of â€Å"American† youths to integrate and participate in the society that they have thus far known and accepted as their own. Even though the Dream Act attempts to specifically nurture the life of migrant youths, this could also motivate more illegal

Value Stream Mapping and Interviews with Michigan Steel Company Term Paper

Value Stream Mapping and Interviews with Michigan Steel Company - Term Paper Example The production lead time is also reduced by analyzing the primary data obtained from observing actual processes in the company’s factory. Further, this paper discusses the methods employed in the analysis and drawing of Michigan Steel Company’s value stream map. These methods are vital in the calculation of the cycle time, changeover time and uptime. The number of shifts for each worker and EPE (every part every) is also calculated. The target number of pieces is also recommended. Finally, the paper concludes by giving the results of the entire project and further discusses them giving recommendation where necessary. The value stream technique is mostly used in the design and analysis of information and material flow that will bring a product or service to the final customer or consumer. Furthermore, the technique also aims at using minimal resources whilst maximizing production. In the analysis of this one is required to draw a current state map that illustrates the whole value stream mapping technique employed. This paper shall embark on discussing the current state map for the Michigan Steel Company and evaluate is value mapping technique. In order to successfully analyze the technique at Michigan Steel Company, the entire chain of steel production is broken down into discrete levels of production and information flow. The step by step flow from production is evaluated and the lead and processing time taken to complete the production is also determined. The route taken by the product until it reaches the State Street Assembly (customer) is also illustrated in the Michigan Steel Company’s current state map situation. This paper shall then discuss this process’s methods, results and efficiency. The biggest problem met by Michigan Steel Company was the relevant optimal lead time for the entire production process. This necessitated the team to set up objectives that are oriented towards goal  achievement.  

Business legal issues. Brandon Burton, Leslie Gaines, Eric Essay

Business legal issues. Brandon Burton, Leslie Gaines, Eric Defrancisco, David Butler, Sanjeev Dube - Essay Example In this case, the mention of his disability as a concern may be construed as prejudice against the physically disabled as a class. The discrimination is made more apparent by the fact that the position being applied for is a managerial one, a job that requires more of mental skills rather than physical capabilities. There may be instances, however, when it is proper to express concern that physical disability may get in the way of the discharge of the duties of the position. When the job requires physical dexterity and the application of manual skills, then clearly the situation of a paraplegic will be a hindrance to the discharge of the function. There are many such instances when the specification of physical attributes for a particular job is accepted as normal and regular, such as requiring airplane attendants to be of a certain minimum height to be able to reach overhead baggage compartments, or ballet dancers to be male to fulfill a particular dance role. Ethnicity or racial or igins may sometimes be necessary for assignment in certain parts of the world, to reduce the threat of personal risk to the individual, or to increase the company’s acceptance in that culture. ... (2012). â€Å"Dallas company sued for disability discrimination.† Retrieved from: http://www.houstonemploymentlawattorney.com/2012/06/dallas-company-sued-for-disability-discrimination.shtml Response to the post of Student 2: Leslie Gaines Reading through the original report of the case, it is mentioned that the company believes the claims to be baseless, â€Å"but will investigate them thoroughly.† What is happening in this case, or at least what the company wants to portray, is that the assignment of non-whites to lower-paid â€Å"back of the house duties† (if it is true) is the decision of the local branch management and is not a policy of top management. In either case, the company has a duty of restitution to the non-whites, not only in monetary terms, but in terms of restoring their dignity and self-esteem. Then if indeed the branch management is culpable, then they should be dealt with by the top executive, together with articulation of a clear statement ag ainst discriminating practices (Daft & Marcic, 2012). It is clear that the company does not claim that the restaurant is trying to maintain a high-end image so it does not assign non-Caucasians as servers; it is the plaintiffs who allege this (Wildeboer, 2012). Had this been the defense of the firm – that it seeks to maintain an image – then it would be tantamount to an admission, and the force of the law should be brought to bear upon it for racial discrimination. Nor does the report say the 26 plaintiffs were qualified. If they are, the firm should be held accountable by the principle of command responsibility. However, it must first be proven that there are and have been absolutely no non-white servers, and that all non-whites, despite being qualified for the front-end, are summarily

Management Strategy Assignment Example | Topics and Well Written Essays - 250 words

Management Strategy - Assignment Example Lynch (2003) asserts that resource based strategy of the firm uses unique knowledge base that is creatively applied on all tangible and intangible assets to above average return. Thus, various business processes, innovative products and services, human capital etc. become strong elements of RBC. Apple, Huawei, GM, Wal-Mart etc. are exemplary examples that have been able to maintain their market position through innovative products and services across the globe. Apple and Huawei have creatively evolved new features and techniques in mobile devices to suit the changing requirements of the new generation. The technology driven resource based strategy that exploits the information to give distinct differentiation to its products and gain leverage. GM has innovated green technologies to make its cars environment friendly. Wal-Mart, on other hand, has judiciously used I/O framework to enhance efficiency of its business processes. The information vis-Ã  -vis customers’ changing preferences are used both in new product develop and value addition as well as in logistics to give quality services to its customers and maintain its niche market

MGT499 Module 1 Essay Example for Free

MGT499 Module 1 Essay Harley Davidson has been around the United States since 1903 and have always found a way to stay productive and current in this country, they have made huge strides to maintain their quality and trust in their customers. In this day and age even that may not be enough to supplant a company’s financial security and Harley Davidson may have to emphasize more on sales outside the USA. Harley Davidson’s quality mission is that they value the deep emotional connection that is created with their customers through their products, services, and experiences. They are fueled by the brand quality and trust that their customers place in the company to deliver premium quality and the promise of a fulfilling lifetime ownership experience. Harley Davidson exemplifies this commitment by embracing a culture of personal responsibility and stewardship for quality in everything they do. Harley Davidson fulfills these dreams by their corporate value of providing motorcyclists an expanding line of motorcycles and branded products and services to a selected market segment. Harley Davidson’s strategic vision is the delivery of unique motorcycling experiences, as individual as are their customers. The experiences could be as basic as a Sunday morning coffee, or a full moon beach ride. This corporate passion of delivering unique customer experiences is the core of their strategy and the reason for their competitive edge. This corporate passion of delivering to their main stakeholders includes customers and employees. Since the employees of Harley Davidson are motorcyclists themselves, their commitment to delivering an unforgettable motorcycling experience is the reason for the competitive advantage the company enjoys with a distinctive and innovative legendary motorcycling product line. When employees feel like a participant they will have a mutual goal: the long term success of the Company. (Fred, 2008). This is one of the area’s Harley Davidson has placed special emphasis on. With restructuring there assembly lines it became a necessity to know if something was not correct in the process, open communication allowed employees to communicate with leaders to resolve issues quickly, minimizing loss. Employees are also encouraged to participate in Harley Davidson Learning Center for its employees; the center was created after restructuring of the workforce to create semi-autonomous workgroups. The center is dedicated to lifelong learning, but is also used to hone skills, learn new skills and if needed remedial training. Harley Davidson customers are a cult. They are as unique as the motorcycles they ride. The passions of their experiences as bikers have made permanent inroads in the landscape of the United States. They are a part of Americana popular culture. They have inspired rock songs, political frame of references, and have been strategically aligned to a sense of freedom, which is the American symbol. The needs and goals of the employees at Harley Davidson are being met. Open communication at all levels is used as a major key to achieving teamwork and employee participation. When employees feel like a participant they will have a mutual goal: the long term success of the Company. (Fred, 2008). This is one of the area’s Harley Davidson has placed special emphasis on. With restructuring there assembly lines it became a necessity to know if something was not correct in the process, open communication allowed employees to communicate with leaders to resolve issues quickly, minimizing loss. Consumers are actually fulfilling more and more dreams, which is evident by increases in sales. There are many reasons for this, Harley Davidson listens to its consumers and values their input. They also created the Harley Owners Group (HOG) so that the Company can receive feedback from its riders and continue to make their experiences better and better by improving the products. â€Å"They conduct four US national rallies, two touring rallies, and 44 state rallies. † (Fred, 2008). Where they can receive feedback from riders and enjoy some customer bonding as they share in the excitement of riding. Harley Davidson just made major improvements in 4 key areas of their current line of motorcycles, with the input of their riders. Control; Larger engine, brighter lights, and Anti-locking Braking System. Infotainment; color touch screen radio with Bluetooth, GPS, and CB communication all in one unit which can be controlled by voice commands, allowing a rider to keep both hands on the bars. Feel; redesign of Fairings, improved passenger room with back rest and arm rests. Style; Redesigned trunk and saddle bags, with on touch latches, lighter wheels and intuitive hand control switches. â€Å"Weve been one with our riders and dealers for 110 years, and were now doing a much, much better job bringing their insights and needs into great new bikes; and getting the job done 30 percent faster so they can enjoy it all sooner! The worlds best – and best-selling – touring bike just got a whole lot better because of the inspiration of our riders and the talent and dedication of our employees. † (Hoyer, 2013) My recommendation to the executives of Harley Davidson would be to inspire an international campaign of freedom. To launch an international marketing campaign and highlight the individual countries landscapes with passionate riding experiences unique to that country. Since the employees of Harley Davidson are motorcyclists themselves, I would recommend that the corporation employ motorcyclist employees in each of the international companies to work and design a line for each of the individual country markets. The competitive advantage to Harley Davidson has always been about the delivery of unique experiences, the marketing and production campaign in each of the individual countries would succeed if they are able to deliver to that country’s stakeholders an unforgettable motorcycling experience. References: Harley Davidson. (2012) Annual Report 2011. Retrieved from: http://media. corporate-ir. net/media_files/IROL/87/87981/HD. pdf Fred, (2008). A case study of Harley Davidson’s business practice. Infotechdesign. Retrieved from: http://infotechdesign. net/itd/a-case-study-of-harley-davidsons-business-practices. htmlÃ'Ž

Formal Reality And Objective Reality

Formal Reality And Objective Reality To begin this approach, Descartes introduces formal reality and objective reality. Formal reality is said to be what humans can actually see and prove to be their senses, and objective reality is what is in their minds. Descartes goes on to say, Hence it follows, both that nothing can come from nothing, and that what is more perfect cannot derive from what is less perfect (Third Meditation 29). In this quote Descartes believes that nothing can come from nothing: a person cannot get one from zero; for an effect to happen their must be a cause, and an effect must have as much reality as its cause, as so, something that is perfect cannot come from something that is less perfect. For example, it is not possible to have hot water without a thing that creates heat. Also, electricity is what causes a light bulb to turn on, but a light bulb cannot cause electricity. After realising this, Descartes uses this argument to sum up how the idea of God came to be. He believes that he is not perfect and has limits, so how can the idea of an all knowing and all powerful being with no limits be even thought of. All real ideas come from other real ideas, and even unreal ideas have real qualities in them. A flying pig might not be real, but the idea comes from a pig, and a flying object put together; fairies might not be real, but the idea comes from putting flying qualities to a person. So this Idea of God came from something as real as God, and since there is nothing on earth that is as real as God, we must have been born with the idea, so therefore God exists. In Descartes meditation his premises are structured. One must first accept that the idea of God is more real than anything that is limited; after accepting that, one must accept that an effect cannot be greater than its cause; and after accepting that, one must accept that the idea of God cannot be thought off with out a cause, or without it being real. Once you have accepted all of these it is clear to say that God exists, but if one denies any one of these premises the conclusion fails. Although Descartes believes to have solved the existence of God, many other people such as Atheists have went on to argue that God does not exist. A popular argument against the existence of God is the paradox of the stone: Can God create a stone so heavy that he cannot lift?'(Arguments for Atheisms). God is known to have unlimited power, so if God cannot create a stone more powerful than him, then he does not have unlimited power; if he is able to create such a stone that he cannot lift, then he still does not have unlimited power. So either way God is not all powerful; something that is all powerful can do everything, and since God cannot do everything, God does not exist. Though this argument is seemingly legit, there are many arguments that proves its falseness. Descartes believes that God can do the logically impossible, so God can make two plus two equal five. However, Thomas Aquinas (A Christian philosopher) believed that God can possibly do anything, but he cannot go against the laws of logic. With Aquinas argument, it proves that God cannot do something, which has to be false because God has to be able to do everything. So if we go with Descartes argument that God can make two plus two five, it also means that God can Create a stone that he cannot lift, and then lift it. This argument may seem difficult to understand, but Descartes tells us not to try and understand God because it is not possible. This proves that the argument of the paradox is false, a simple way to prove that it is false, is that God is known to be a spirit that cannot be seen, but here the paradox argument gives God human qualities (The Paradox of the Stone). The stone argument failed to prove that God does not exist, so Descartes argument about Gods existence still stands. But looking at it in a different way, say that a person is stuck on an island, and this person cannot escape, so he/she builds some type of shelter to be protected from the bad weather such as, rain and cold temperatures. Now, this person does not know what perfect is, but while building this shelter, this person will not attempt to make it bad seeing he/she wants good protection; this person will attempt to make a perfect shelter, so can the idea of something perfect not come from our selves? Descartes answer to this question would be no: everything has its opposites, and one opposite cannot be without the other. For example, there cannot be heat without cold, and one would not know what pain is without joy. Which must mean that God exist because humans are imperfect, and the opposite of imperfect is perfect. It is very difficult to disprove Gods existence, but if God exists, and everything has a cause; what caused God? Scientist hold this point strongly as to disprove the existence of God. Descartes, however, says not to try and understand God, but his whole meditation attempts to find if God exists which is trying to understand. Descartes somehow goes around the question what caused God. In the world we live in today, one should not be surprised if one does not believe that God exists. It is simple, in our society proof is necessary; if a close friend was to threaten to kill themselves, it would not be all that believable, but when the friend shows a weapon to be used, then the belief will increase. Also, one cannot go to a court room and say to a judge, He is the murderer, you might not understand your honour, but he killed an old lady. One would need some type of convincing proof to prove that someone is a murderer. It is just how the world works. Descartes believes that God is not a Deceiver, and that God is supremely Good, if it is so, why does God allow suffering? If a father, that is known to be good, one day sees his twenty three year old son on the street begging for food and money, and the father realizes this and walks away, is it reasonable to say that the father is good? Not at all, in fact one would believe that the father has abandoned his son. This argument has been used countless times to disprove the existence of God. Arguments can go both ways, and this argument about the existence of God is ridiculously difficult. One can conclude that God exists, but until physical evidence or something more real is shown, saying that God exists will just be a theory, at least in this world. Perhaps if one was in a world where there is simply one religion and one belief, then the idea of a God would be easy to believe, even if it is false. So Descartes has reasonable ideas of the existence of God, but as long as we are in a world filled with many different race, religion, and ideas, Descartes argument about Gods existence will always be plausible.

Secretors And Non Secretors In Human Population Biology Essay

Secretors And Non Secretors In Human Population Biology Essay Human population can be categorized into secretors and non-secretors. They are categorized on the basis of presence or absence of the blood group antigens (A, B and H) in the body fluids and secretions, such as saliva, sweat, tears, semen, serum, mucus present in the digestive tract or respiratory cavities etc. Secretors are individuals that secrete blood group antigens in their body fluids while non-secretors are the individuals that do not secrete them in their body fluids and secretions. It is a known fact that ABO blood type is controlled by blood type coding genes present on the chromosome 9q34 but the secretor status of an individual is decided by interaction of a separate gene (called secreting gene) with these blood type genes. The presence of the secreting gene in a persons genome makes him a secretor and absence makes him a non secretor. The gene is designated as (Se) for Secretors and (se) for Non-secretors and it is entirely independent of the blood type A, B, AB or O. The individuals secreting antigens in the body fluid are designated as ABH secretors in blood banks. Individuals having O blood group secrete antigen H, A blood group secrete A and H antigens, B blood group secrete B and H antigens in the fluids. A secretor gene helps a person to gain a degree of protection against different environmental conditions especially the micro flora of a particular environment and also the lectins present in them. It helps them in promoting the growth of friendly, stable blood type intestinal bacterial ecosystem which depends on the blood type antigens present in the mucus of an individual. Secretor status does alter the carbohydrates present in the body fluids and their secretions and hence it also affects and influences the attachment and persistence of the micro flora present in the body. Secretors are at a higher advantage than non-secretors. Non-secretors have a potential health disadvantage. They possess many metabolic traits such as carbohydrate intolerance, immune susceptibilities. Different tests are available for determining an individuals secretor status. Most common test uses saliva or other body fluids of an individual for testing the secretor status. These tests are based on the princi ple of Agglutination Inhibition where the antigens are neutralized by the corresponding antibodies so that these antibodies will not be further be available to neutralize or agglutinate the same antigens residing on the red blood cells. ELISA could also be used for determining the presence of the secreted Lewis antigens in the saliva or other body fluids. Statistics Series, Place Reference Number Tested % Secretor % Non-secretor Frequency Frequency Negroes,New York (5) 178 61.2 38.8 0.38 0.62 Danes,Copenhagen (6) 263 74.0 26.0 0.49 0.51 Japanese,Japan . 424 75.7 24.3 0.51 0.49 Germans,Berlin (7) 363 78.0 22.0 0.53 0.47 Poles,Poland (8) 88 79.4 21.6 0.54 0.46 Whites, New York (9) 74 82.4 17.6 0.58 0.42 Finns, Helsinki (10) 196 86.3 13.7 0.63 0.37 American, Indians,New Mexico (11) 69 98.5 1.5 0.88 0.12 American, Indians, Utah (12) 79 100.0 0 1.00 0 The alleles Se and se differ in the frequency and have an anthropological value. They occur in different frequency in different populations. They have a high frequency in the American Indiana and a low frequency in the southern Indians. In US 20% of the population is secretors whereas 80% of the population consist of non-secretors. The fusion allele of the FUT2 (secretor type alpha(1,2)-fucosyltransferase) gene at a high frequency and a new se385 allele in a Korean population SECRETOR AND NON-SECRETOR A person secreting blood group antigens into the body fluids and other secretions like saliva, semen, tear, mucous in the digestive tract and respiratory cavities are named as secretors. In similar terms they put their blood type antigens in the body fluids. They secrete antigens according to their blood type, A secrete antigen A and H, B secret antigen B and H, O secrete antigen O and AB secrete A, B and H antigen. Secretors expresses Lewis b (Leb) antigens on the RBC where as non-secretor expresses Lewis a (Le a) on their RBC.These antigens in the body fluids give additional protection to the individual against the various microorganisms and the lectins present all around us. 15- 20% of the population consists of non-secretor. These individual fail to secrete the blood group antigens in their body fluids hence they become susceptible to bacterial and superficial yeast infections. A large no of them sometimes also suffer from the autoimmune disorder. This could also be correlated with the secretor and non-secretor phenotype. The body secretions of secretors and non-secretors differ quantitatively and also qualitatively. The type and quantity of the antigens present in it differ among different individuals. In some cases the non-secretors may contain the A and B antigens in the saliva but the quantity is less and even quality is very low hence they have similar functional problem. There are certain properties which are specific for secretors and differ in non-secretors. Some are listed below: Intestinal alkaline phosphatase activity ABH secretor correlates the activity of alkaline phosphatase and serum alkaline phosphatase present in the intestine. Non-secretors have low activity of alkaline phosphatase and serum alkaline phosphatase which is responsible for the breakdown of fat and assimilate calcium. Low molecular weight alkaline is present in both secretors and non-secretors and high molecular weight alkaline phosphatase is present only is secretors. Bacterial flora The ABH blood types influence the population of bacteria residing in the local vicinity of the gut mucin glycoproteins. Bacteria produce enzymes that have the capability to degrade the terminal sugar of ABH blood type antigens and which are consumed as food by them. The B antigen degrading bacteria produce enzyme to detach the terminal alpha-D-galactose and A antigen degrading bacteria produce enzyme to detach N-acetylgalactosamine which are used as a source of food by them. Blood clotting The secretor and the ABO genetics influence each other and influence the variance of the plasma concentration of vWf upto 60%. Raised levels of factor VIII and vWf may cause thrombotic and heart disease in future. Secretors have the slowest clotting time, thinnest blood, least tendency of platelet aggregation, low amount of factor VIII and von Willebrand factor (vWf). The non-secretors have highest clotting time, thick blood, high amount of factor VIII and von Willebrand factor (vWf) and low bleeding time. The blood viscosity is also influenced by the secretor phenotype. Lewis Phenotype Clotting Characteristics Le (a- b-)  Ã‚  highest activity of factor VIII and vWf Shortest bleeding times (especially in A, B and AB) Le (a+ b-) intermediate activity Shorter bleeding times (especially for O) Le (a- b+) lowest activity of factor VIII and vWf Longest bleeding times (especially for O) Lewis Blood Type and Clotting Factors Immunoglobulin levels ABH non-secretors have low levels of IgG immunoglobulin. The secretion of different concentration of different components of the blood group substances is controlled by the secretor gene and it also affects the phagocytic activity of the leucocytes which provides an added advantage to the non-secretors. The leucocytes of the non-secretors possess a greater ingestion power when compared to the secretors. The O and B blood group non-secretors have the highest phagocytic activity. The presence of level of anti-I in the serum of an individual is affected by the ABO group, secretor status and sex of the individual. The secretors females have a high level of anti-I in the serum as compared to the males. The non-secretor have low levels of IgA and IgG antibodies and hence have frequent problems with the heart valve. Genetics and Biochemical pathways The secretion of the blood group antigens in the body fluids and other secretions are genetically influenced by certain allelomorphic genes. Secretor gene contains two alleles Se and se. Se is dominant and hence is present in the homozygous or heterozygous condition in the secretors which lead to the secretion of antigens into the body fluids. se is recessive allele and is present in non-secretors in the homozygous condition. SeSe and seSe produces a dominant secretor phenotype and sese produces a recessive non-secretor phenotype. Basically three genes are responsible for the formation of the A and B antigens. They are namely ABO, Hh, and Sese genes encoding glycosyltransferases which produces the A and B antigens. H antigen present in the individual with O blood group is the precursor for the formation of A and B antigens. H antigen act as a backbone on which the A and B antigens are built up. The O gene is considered as amorphic. The allele Hh and Sese reside on each locus and are closely linked together. It is also suggested that one of the allele has arisen by the gene duplication of the other. The H allele is responsible for the production of H antigen on which antigen A and B are built. The second allele on the same locus is really rare. The product related to this allele hasnt been discovered yet and hence it is considered as amorph. The oligosaccharide responsible for the formation of the A and B antigen can exist in a simple linear fashion or a complex branched fashion. Infants A, B and H antigens contain high amount of linear chained oligosaccharide whereas oligosaccharides present in an adult contain high amount of branched chained oligosaccharides The A and B antigen is synthesized from a common intermediate known as substance H. The conversion is carried out by the addition of a sugar molecule to the non reducing end of the H oligosaccharide chains. This addition affects the reactivity of H antigen. The ABH substances are secreted in the Urinary respiratory tract, gastrointestinal tract by mucous glands residing there. The secretor gene regulates the synthesis of blood group antigens in the superficial glands of gastric and small intestinal mucosa. The secretors and non-secretors produce A and B substances which are basically glycoproteins in pylorus and Brunners glands and produce A and B substances those are soluble in alcohol and glycosphingolipids in nature. The secretors also produce ABH substances in the prostate and lactating mammary glands. The secretion of breast is rich in H substance but poor in substance A and virtually absent in substance B. The synthesis of these substances in the exocrine acini of pancreas and secretory cells of sweat gland is not controlled by the secretor gene. The blood groups substances were also detected in the collecting tubules and calyxes of the secretors but it could not be concluded that whether they are produced by the kidneys or are generally excreted. These secretions were noticed in the eight to nine weeks old salivary glands and stomach and later it appears throughout the gastrointestinal tract. Glycosphingolipids carrying the A or B oligosaccharides are present on the membranes of RBCs, epithelial and endothelial cells and are also present in the plasma in the soluble form. The glycoproteins carrying the similar A and B oligosaccharides are responsible for their activity in the body fluids. In the body fluids they are present in the secreted form. The A and B oligosaccharides which do not contain the carrier proteins are present in the milk and urine. The chromosome 19 containsFUT 1 and FUT 2 genes which code for fucosyltransferase. FUT genes numbered from 1-7 and form clusters which are responsible for the production of enzymes called as fucosyltranferases. The cluster is located on chromosome 19q13.3. Fucosyltranferase helps in the formation of fucose moiety which is added to the H antigen and further gylcosylate the A or/and B antigens. H antigen is a basic blood group antigen present in each and every human being but the content varies in different individuals of the same ABO group. A general pattern indicates that its strength varies as O>A2>A2B>B>A1>A1B. Water soluble H antigen has been demonstrated in the saliva and the body fluids of the individuals.H antigens are fucose containing glycan units which are present on the glycolipids or glycoproteins residing on the erythrocytes membrane or in the secretions. The fucosylatedglycans are the substrate for the enzyme glycosytransferases that are responsible for the formation of the epitopes for A, B and Lewis blood group antigens. Secretors contain both the alleles whereas non secretor contains the null allele for FUT2 gene. The FUT 2 gene codes for fucosyltranferaseenzyme in the exocrine tissues which lead to formation of antigens in the body secretions and body fluids. The A and B genes produce glycosyltranferase that add sugar to oligosaccharide chains that is converted to H antigen. The H antigen are constructed on the oligosaccharide chain. The oligosaccharide chains could be of two type : Type 1 and type 2. 1 carbon of the terminal 6-carbon sugar b-D-galactose (Gal) is linked to the number 3 carbon of subterminal  N-acetyl-glucosamine  (GlcNAc) in Type 1 chains and to the number 4 carbon of GlcNAc in Type 2 chains. The glycosphingolipids present in the plasma and on the membranes of glandular and parenchymal cells and glycoproteins present on the cell surfaces or body fluids carry either the type 1 or type 2 chains. The glycolipids antigens present on the RBC contain type 2 chains. A gene-specifies N-acetyl-galactosaminyl-transferase and the B gene-specifies galactosaminyl-transferase and add   GalNAc   and  Gal   respectively in alpha (1-3) linkages to the same Gal which is acted on by the H gene transferase. The H gene produces fucosyltransferase that add fucose to the terminal Galactose molecule of type 2 chain. It forms an alpha (1-2) linkage. A and B antigens are constructed when the A and B transferases attach respective sugars to the type 1 or type 2 chain substituted with Fucose. The A alleles encode UDP-GalNAc: Fuc alpha1->2 Gal alpha1->3 N-acetyl-D-galactosaminyltransferase (alpha 1->3 GalNActransferase or histo-blood group A transferase). The B alleles encode UDP-Gal: Fuc alpha1->2 Gal alpha 1->3 galactosyltransferase (alpha 1->3 galactosyltransferase or histo-blood group B transferase). O alleles encode proteins without glycosyltransferase function The secretor gene FUT2 located at 19q13.3 and codes for the activity of the glycosyltransferasesin concert with the FUT1 gene coding for H antigen, needed to assemble both the ABO and Lewis blood groups.They are active in places like goblet and mucous gland cells which interact with each other and lead to secretions of antigens in the fluids. The expression patterns of both the genes are different. The FUT1 (H) gene is dominantly expressed in the erythroid tissues which lead to the formation of the H enzyme whereas the FUT2 (secretor) gene is expressed in the secretory tissues and lead to the formation of secretor enzyme. The product of the H enzyme or H gene resides on the erythrocytes and product of secretor gene resides on mucins in secretions. If an individual lack these alleles, he/she will not be able express the above active enzymes therefore they would lack the substrates for the A or B glycosyltransferases and hence they would not express the A and B epitopes. Relationship of ABH Secretor status and Lewis system Lewis typing is sometimes used for the de facto determination of the ABH secretor status. The production of Lewis antigens is genetically controlled. Individuals possessing the Lewis (Le) gene would produce the Lewis antigens which are carried in the plasma by different substances and are absorbed onto the Red blood Cells present in ones blood. The ABO determinants and H/h blood groups determinants are structurally related to Lewis blood determinants. FUT1 provide the glycans for glycosyltransferases which convert Lewis antigen to ABH antigens. FUT2 allele is expressed in the secretor and is responsible for the expression of type1 H determinant. The secretors convert their Lewis a antigen to Lewis b therefore they are (a-b+) and the non-secretor are (a+b-) as they lack the FUT2 responsible for glycosyltransferase which could convert Lewis a antigen to Lewis b antigen. Lewis (Le) gene and Secreting (Se) gene interact with each other. Initially Lewisais formed and if Se gene is absent in an individual the Lewisa substance is absorbed on the RBC and the individual is typed as Lewisa but in secretors the Se gene controls the activation of the H gene which causes addition of an additional sugar to Lewisa which convert it to Lewisb. Secretors contain both Lewisa and Lewisb in their plasma but absorb Lewisb preferentially on the red blood cells and the individual is typed as Lewisb. Hence we could interpret that presence of Lewis gene would type an individual as Lewisa positive or Lewisb negative or vice versa. An individual could not be positive for both. A person containing both Lewis gene and Secreting gene are typed as Lewisa negative and Lewisb positive whereas a person having the Lewis gene but not the secretor gene is typed as Lewisa positive and Lewisb negative. Individual who does not have Lewis gene regardless of secretor gene is typed as Lewisa negative and Lewisb negative. Note: Lewis Double Negative (LDN) is a sub type of non secretors but Lewis typing cannot be used for them to determine the ABH secretor status. Detection methods The presence and absence of the antigens in the body fluids could be detected by Agglutination Inhibition and Lewis typing. Agglutination Inhibition test could be divided into two parts:- Part I Antibody Neutralization: To determining ones secretor status, the saliva of the individual is mixed by the antiserum (Anti-A, Anti-B or Anti-H) available commercially. In secretors the soluble substances i.e. blood group antigens will react with the antibodies present in the antiserum and will get neutralized. Part II Agglutination Inhibition: The bed blood cells obtained commercially are added to the test mixture. In secretors agglutination of the RBC do not take place as no free antibodies are available to agglutinate them. All the antibodies have reacted with the soluble antigens present in the saliva whereas in non-secretors agglutination would occur upon addition of the RBC as no blood group antigens are present in the saliva so antibodies present in the antiserum are not neutralized and hence would be free to react with the test RBC cells which are added to the test mixture. Hence agglutination is a negative test for secretor status and positive test for the non-secretor status. Note: Anti-H lectin containing phytohaemagglutinin virtually specific for human RBC. Thirteen Cucurbitaceaespecies have been investigated for the anti-H activity present in their seed lectins. Lectins has been extracted and purified from Ulexeuropaeus seeds. It could be used to demonstrate the H secretor status of blood group O individual and also for subgrouping the blood group A individuals. Lewis typing: Individuals carrying the Lewis gene produce Lewis antigens that are carried by the plasma and are also adsorbed on the red blood cells. Lewis antigens do not reside only on the red blood cells. Initially the gene gives rise to Lewisa. If Se gene is present it activates H gene which interact with the Lewisa and add a sugar to Lewisa and hence get converted it to Lewisb. Both Lewisa and Lewisb in present in the plasma of the secretors. If the Se gene is not present then the Lewisa substance is adsorbed on the red cells and individuals are typed as Lewisa. The secretor status of an individual could be determined with help of Lewisa and Lewisb antibodies mixed with an individuals saliva and observing the agglutination macroscopically. Disease Susceptibility among Secretors and Non-secretors Digestive system Non-secretors are more prone to the diseases caused by the oral bacteria in the digestive system of an individual. It includes ulcers, celiac diseases gastric carcinoma pernicious anemia etc. It could lead to dysplasia or increase in the number of cavities present in the digestive tract. Non-secretors are less resistant to the infection caused by Helicobacter pylori which could lead to the formation of peptic and duodenal ulcers. It could easily colonize and cause inflammation in the non-secretors. The non-secretors lack the blood group antigens in the mucus secretions therefore H.pylori attach to the walls of the digestive tract and cause infection. The secretors have a tendency to secrete free ABH antigens in their intestinal secretions which effect the bacterial and lectins adherence to the microvilli present in the gut. The secretors produce these antigens and act as a competitive disadvantage from preventing H.pylori attachment. These antigens act as a decoy in the secretors whi ch prevent them from attaching with the host tissues. The non-secretors also show a lower IgG immune response to the H.pylori. They have excessive rate of bleeding, perforation and development of stomach ulcers but correlation between these complications and the secretor status have not been documented yet. The non-secretors are not able to turn off the digestive enzymes and hence they produce large amount of enzyme pepsin and hence are more prone to duodenal ulcers. 50% of the duodenal ulcers are present in non-secretors. 30-40% of group O individuals are affected by the duodenal ulcers and 15- 20 % are affected by the gastric ulcers. They act as a multiplicative risk factor with the gene coding for hyperpepsinogenemia I which impact in the risk of duodenal ulcers. Group A individuals have a higher tendency of having gastric cancer and pernicious anemia. Statistics shows that 20% of the group A individuals are affected by gastric cancers and 25% are affected by the pernicious anemi a. Oral pathology The non-secretors are more prone to oral diseases like mouth and esophagus cancer, epithelial dysplasia etc. They have more cavities than secretors. Diabetes The ABH non-secretors and Lewis negative (Le a-b-) individuals have a high risk of developing insulin dependent diabetes or complications arising from diabetes. Secretors with juvenile diabetes have a low chance of developing retinopathy. The ABH non secretors which are affected by insulin dependent diabetes mellitus the mean level of C3c and C4 is lower as compared to ABH secretors. Metabolic Syndrome X The Lewis negative men are predisposing to syndrome X and prothrombic metabolism. They have high levels of BMI, SBP, triglycerides and low rather fasting levels of serum insulin and plasma glucose. This relationship is not true for women and is only applicable for the men. Respiratory System   Secretors have an added protection against the harmful environmental assaults directed towards our lungs and as usual non-secretors have a health disadvantage. They are over represented among the people suffering from influenza viruses A and B, rhinoviruses, respiratory synsytial virus and echinoviruses. The secretors who are miners or smokers do receive a protection against the disastrous effects of the cigarette smoking. Asthma is very common among the individuals working in the coal mines. Upon research it was concluded that asthma among them is also related to the non-secretor phenotype present in them. The non-secretor has a tendency to snore and are more prone to COPD (Chronic Obstructive Pulmonary Disease). Heart disease The ABH non-secretor phenotype have a high risk of developing myocardial infarction and Lewis negative individuals have a high risk of developing chronic heart disease (CHD) and also ischemic heart disease (IHD). They contain high levels of triglycerides. Alcoholism has a positive interaction with the Lewis negative individuals. Alcohol consumption is protective in these individuals. Autoimmune Disease   Autoimmune disorders such as ankylosing spondylitis, reactive arthritis, psoriatic arthropathy, Sjogrens syndrome, multiple sclerosis, and Graves disease are more prone in non-secretors. The ABH non-secretors affected with graves disease produces high levels of antitubulin antibodies as compared to secretors and are unable to produce the water soluble glycoproteins in the saliva. Fetal Loss and Infertility ABO antigens are also found on the sperm of the secretors. These are obtained from the seminal secretions present in them. ABO incompatibility could exist between the wife and husband if could affect the fertility of an individual. This issue has not been properly studied and is therefore under research. Rheumatic Fever The secretors and group O individuals are resistant to Rheumatic fever and more number of cases have been recorded in the non-secretors. Secretor status could also determine whether the rheumatic fever would be followed by streptococcal pharyngitis or not. Neisseria species The non-secretors who do not produce water soluble antigens in the saliva are at the risk of getting infected by Neisseria meningcococcal disease. The immune capabilities of the secretor provide a relative protection in the secretors. The ABH non-secretors produce low level of anti-meningococcal salivary IgM antibodies which provide protection to the secretors against the microorganism. Candida species Non-secretors are barriers of candida species and therefore are frequently affected by the candida infections. The glycocompounds secreted by secretors in the body fluids inhibit adhesins present on the yeast which are responsible for their adhesion with the body tissues. This leads to the development of the chronic hyperplastic Candidiasis. Statistics shows that 68% on the non-secretors are affected by chronic hyperplastic candidiasis. Non-secretor women are affected by recurrent idiopathic vulvovaginal Candidiasis. An individual with a combination of non-secretors and absence of Lewis gene are at relative risk of developing recurrent idiopathic vulvovaginal Candidiasis. Tumor Markers The individuals with inactive Se (se/se) alleles and homozygous active Le alleles (Le/Le) allele have a highest mean value of CA19-9 tumor marker. The Lewis negative individuals irrespective of Se genotype have negative values for CA19-9. The Lewis negative individuals have higher mean value for DU PAN-2 as compared to Le-positive individuals. We can conclude that CA 19-9 marker is not an appropriate tumor marker for Le-negative individuals but DU-PAN-9 is an appropriate tumor marker. Bacteria Urinary Tract Infections Non-secretors are at a higher risk of getting recurrent urinary tract infection (UTI) and renal scars as compared to secretors. This susceptibility is higher among negative Lewis subset. Statistics of a study done on women affected with recurrent urinary tract infection stated that 29% of the non-secretor women were affected by UTI and 26% of Lewis (a-b-) women were affected by the UTI. The non-secretor phenotype and blood group B and AB phenotype work together to increase the risk of UTI among women. Women and children suffering from renal scarring with and without the antibiotic treatment for UTI are prone to UTI and pyelonephritis. 55-60% of non-secretors develop renal scars and 16% on secretors develop renal scars. C-reactive protein levels, erythrocyte sedimentation rate and body temperature are higher in the non-secretors that in secretors with recurrent UTI. Conclusion It concludes that there exist a statistical association between the individuals blood-group secretor phenotype and the diseases they are susceptible to. So knowing your secretor status is advantageous as we can use the nutritional supplements more intelligently and effectively. It also makes us aware of the diseases, illness and metabolic dysfunction we are prone to, difference in the levels of intestinal alkaline phosphatase activity, propensities towards blood clotting, tumor markers and different ingredients of breast milk so that we can manage them before hand and would be prepared for them in the near future.

The Importance of Childhood Vaccination Essay -- Medicine Health

Since the introduction of vaccinations, medical science has managed to all but eliminate many formally fatal and debilitating childhood illnesses in countries where the immunization of children is nearly universal. Diseases such as measles, mumps, diphtheria, rubella and polio have been relegated to a marginal status in developed countries with active immunization campaigns; smallpox is actually considered to have been completely eliminated from the earth, without a single case having been reported since roughly 1979 (â€Å"Childhood†). Largely centered around a study published in 1998 in the British medical journal â€Å"The Lancet†, there has been an upsurge in concerns of the safety of vaccinations and a resulting decrease in their usage, which has lead to a somewhat anachronistic return of these diseases. While some parent's concerns over the safety of vaccinations are based upon the well-intentioned desire to keep children safe from autism, the act of not vaccinat ing children actually causes far greater damage by exposing them to acquiring potentially life-threatening illnesses and removing a critical link in the chain of herd immunity. Over the last 12 years, a growing population of parents have chosen to avoid immunizing their children with the misguided belief that they are protecting their children from the specter of autism. One of the most common concerns in this vein centers around the MMR (Measles, Mumps, Rubella combination) vaccine. The concern over the MMR vaccine began when â€Å"In 1998, Andrew Wakefield and colleagues published a paper in the journal â€Å"The Lancet†. Wakefield's hypothesis was that the MMR vaccine caused a series of events that include intestinal inflammation, entrance into the bloodstream of proteins harmful ... ... In Context. Web. 28 Oct. 2010. Deer, Brian. "MMR doctor Andrew Wakefield fixed data on autism." The Sunday Times. Times Newspapers Ltd , 8 Feb. 2009. Web. 28 Oct. 2010. â€Å"HAZLEHURST v. SECRETARY OF HEALTH AND HUMAN SERVS.† 604 F.3d 1343 (2010). Leagle.com. Leagle, Inc. Web. 28 Oct. 2010 "Noncompliance with Mandatory Vaccinations Threatens Community Health." Should Vaccinations be Manditory? Ed. Noà «l Merino. Detroit: Greenhaven Press, 2010. At Issue. Gale Opposing Viewpoints In Context. Web. 28 Oct. 2010. "Vaccine Risks Are Outweighed by the Risks of Not Vaccinating." Should Vaccinations be Manditory? Ed. Noà «l Merino. Detroit: Greenhaven Press, 2010. At Issue. Gale Opposing Viewpoints In Context. Web. 28 Oct. 2010. "Vaccines." Current Issues: Macmillian Social Science Library. Detroit: Gale, 2010. Gale Opposing Viewpoints In Context. Web. 9 Nov. 2010.

Essay --

King Lear was one of Shakespeare’s lifetime popular work, and one of his most powerful works. Many people believe it was Shakespeare’s best tragedies ever committed. In this paper I will be giving a brief summary of the story as it unfolds; and a character analysis from the main characters are going to be presented as well. King Lear of Britain decided to step down from his throne, leaving his kingdom to his three daughters. Before the king divides his kingdom the king tests. The three daughters had to express their love for the king; his two oldest daughters Goneril and Regan sweet talk the king for a part of the kingdom. Cordelia the youngest and Lear’s favorite remained silent and told the king that no word can express her love for the king. King Lear became furious for not hearing the sweet words he was expecting and disowns Cordelia. She then leaves the country to marry the king of France. (Mabillard) Lear’s most trusted counselor Earl of Kent is also banished for defending Cordelia. Kent seeing danger in the Kings oldest daughters leads him to put himself in disguise as a servant. He remains close to King Lear to protect him from Goneril and Regan who decides to usurp their father’s kingdom. Meanwhile the Earl of Gloucester is also dismayed by the events happening in his household. Edmund his illegitimate son told Gloucester that Edgar his legitimate son is trying to kill him. This being a lie by Edmund to obtain his brothers birthright. (Mabillard) When Gloucester realizes that Lear’s daughter have turned against him he decides to help him. Regan and her husband Cornwall discover Gloucester helping Lear and accuse him of treason, bling him and turns him to wonder the countryside. He later is found by his disguised son ... ...r father and turned against him. They plotted their father’s death with Edmund. He was the son of Gloucester; he was evil and wicked. Not only does he plot the king’s death but his own father’s death too blaming it on his brother. Edgar was the opposite of his brother Edmund. He is similar to Cordelia; both suffer very much thought out the story. Unlike Cordelia, Edgar does remain alive at the end, and ends up being the King of Britain with Kent and Albany. Kent was King Lear’s loyal companion and counselor. He remains incognito to stay with the king. Kent remained loyal to his king after he realized the king’s daughter’s heartless actions. These were the conflicts King Lear faced throughout the story. Many of the conflicts being from love, power, loyalty, and family. At the end of it all the king died of grief that he could have prevented from the beginning.

Interpretation of the short story “Yellow”

Interpretation of Yellow The short story â€Å"Yellow by Peter Carry Is about being Insecure and how lack of self- esteem can lead a person to suicide. It Is also about changing as a person by gathering enough courage to do It. The story revolves around the mall character Jon, a second-string writer on a London listings magazine, who has been forced on a learn-to-scuba-dive trip in Egypt. Jon is an insecure, overweight man with no willpower, pushing forty and dealing with a midlife crisis. There are also two minor characters in the story, Beret the scuba diving instructor and Brian the other student n Beret's group.The story is told over a few days and mainly takes place in the ocean, the diving school and his hotel, though the hotel is used for nothing more than drinking liquor. The story is told by an omniscient third person narrator that gives us a better impression of Son's way of thinking so we can tell why he in the end chooses to drown himself. Jon is lonely on the trip, the editor didn't pay for his girlfriend to come with him and he Is envious of the other student Brian. â€Å"But he envied Brian his calm, the methodical way he assembled and clambered Into the ear. † (p. 1, l. 9-20) Brian Is a calm, methodical person who Is In control of his own life, unlike Jon. They do not have anything In common besides knowledge of alcoholic beverages, and all conservations just lead nowhere. Son's relationship with his girlfriend does not go well either, â€Å"The silences between them had multiplied, then lengthened into an empty continuum. † (p. 2, l. 54-55). The primary reasons for Son's mid-life crisis are his not-so-well relationship and his suppressed frustration over always being called â€Å"Yellow, a term meaning coward. He thought of his fear and became angry. Well, this would show them he wasn't yellow. (p. 2, l. 128-129). He is sick and tired of his life and tries to drink his misery away but even the alcohol is not on his side, â€Å" He poured more gin, but no matter how much he swallowed it was never enough. † (p. 1, l. 57). In the end, he could only numb his pain by drinking water. Jon actually clings to life at one point, refusing to die. â€Å"Beret grabbed him and thrust in a mouthpiece just before Jon broke the surface, gasping for life, clawing in air. † (p. 3, l. 99-100). This shows that he is not completely ready to let go of his life, even though having contemplated suicide a number of times.He finally transform in the end, he gathers up courage to prove that he is not a coward and let go of his old self. He starts drinking of the ocean water and look back up at himself from below. â€Å"Well, this would show them he wasn't yellow. Then he was calm again and looked back up at himself from below. † (p. 2, l. 128-129). He finally experiences the calm which symbolizes the transformation to his new self. He has left the old ‘Jon' behind and has come the new, free and Ideal ‘ Jon'. Longboats Hughes' â€Å"Suicide's Note†, where the calm face of the river asks for a kiss, fits Jon perfectly, as he accepts the river's kiss of death. Heir nothingness part of an immeasurable emptiness, as if they has shows how he thinks of the depths as an opportunity to leave his life behind. In William Wordsmith's poem, â€Å"Lines composed a Few miles Above Tinder Abbey', where he feels freed by natures living air, blue sky and round ocean Just like how the ocean is Son's beautiful escape way, which releases him from his depressed thoughts ND frees him of his misery. Man vs.. Nature William Wordsmith is a poet who lived during the Romantic era and was heralded as a genius and was the source of inspiration to many.In his poem, â€Å"Lines Composed a Few Miles Above Tinder Abbey', he is saddened by man's inferiority when compared to natures many wonders such as the beauty of a sunset, a raging waterfall and the living air. William Wordsmith felt that nature was an everlasting source of inspiration that knew no boundaries and is astounded by Mother Nature hat fills people up with calming and positive thoughts whereas the human mind chains people with stressful and negative thoughts aiming to hurt and dominate the mind of the individual.Jon and William Wordsmith share the same love for nature because it is their source of inspiration. Jon has grown tired of the Job, his life and the cruel and the indifferent society he lived in. Jon was inspired by the oceans deep dark abyss and felt like this was the place he could get away from it all, the place where he could be at peace.

Modern Drama Essay

Eddie tells Beatrice (his wife) that her cousins have arrived. This pleases Catherine and Beatrice. Beatrice is worried about the arrangements and this is because of Eddie. She says ‘I am just afraid if it don’t turn out good you’ll be mad at me’. This shows that Eddie must have shouted at Beatrice before. This also shows that Eddie takes charge around the house with everything. Eddie has power over everyone in the house. Catherine interrupts and says ‘Well didn’t tell him about me yet. ‘ Beatrice tries to distract Eddie from what she says. But Eddie becomes interested and starts asking questions straight away when he hears Catherine mention herself. Catherine says that she will leave school for a job. Eddie is angry but gets interrupted by Beatrice, Beatrice sticks up for Catherine, and Eddie doesn’t like this. Catherine explains the detail and yet Eddie finds another excuse. He ‘don’t like that neighbourhood over there’. He explains how he wants the best for her and how the men are with young women. The problem is that Eddie thinks that the best thing that Catherine could do is to stay at home with him at home and see or speak with no other men. Beatrice tries to reason with him over the job but Eddie refuses to give in until she confronts him with his desire. She says ‘ you gonna keep her in the house all her life? ‘ Eddie is insulted and disgusted. He becomes angry but when Catherine enters he changes his mood. He doesn’t want to let Catherine see that he does not get along with Beatrice. He gives her what she wants. He agrees with her going to work. This soon gets out of hand and Eddie becomes upset. He uses reverse psychology on Catherine. He tells speaks the opposite of what he wants. He says to Catherine, ‘And then you will move away. That’s life. And you’ll come visit on Sundays, then once a month, then Christmas and New years finally. ‘ This upsets Catherine and without knowing she tells him what he wants to hear. This automatically changes the mood of Eddie. Eddie knows in a way that he has got what he wanted. He changes conversation straight after as before. They start to talk about the day gone by whilst eating their meal. After the meal Eddie asks Catherine when she starts her new job. Catherine knows Eddie is uncomfortable with talking about this. Eddie shows a tear in his eye. Catherine tries to make Eddie feel better by saying that she is not going far. Catherine tries to comfort him. Eddie enjoys this and tries to gain sympathy from her a lot of the time. To settle himself he looks for a cigar. Catherine goes to get one for him and then offers to light it. Eddie feels close with her while she is doing this; he enjoys it while she lights the cigar. Their faces are close and they gaze into each other’s eyes. This shows Eddies true feelings; this is the point where his deep love for her is shown. He looks at her no longer as a relative does but as a lover does. Eddie takes some time to think while Catherine and Beatrice are in the kitchen.

Professional Responsibilities Legislation Essay

â€Å"Teachers must meet their professional responsibilities consistent with the institute’s (IFL’s) professional values.† (IFL) One of the IFL’s many codes of professional practice. Upholding the code of conduct and relevant legislation is the basis for you as a teacher. Among the legislature you need to understand is the importance of the health and safety act (1974) – it says all workers are entitled to work in a safe environment where risks are properly controlled. The HSWA act is also the umbrella under which more specific regulations such as the Manual handling act 1992 (amended 2002) are made. Another fundamental element of workplace health and safety management – and also a legal requirement – is RIDDOR; the reporting of injuries, diseases and dangerous occurrences regulations 1995. Also of great importance – the childcare act 2006, it stipulates every child should get the support they need to be healthy, safe, and enjoy and achieve economic wellbeing. As a teacher you also need to have your own professional values – views, beliefs that will underpin your profession. â€Å"A good teacher is more than a lecturer.† (AMEE 2000) You are no longer a dispenser of information or a walking tape recorder but instead you are a facilitator or manager of the students learning. You are there to ensure all learners have access to the same resources, the same support and you don’t differentiate – instead embrace and respect people’s differences and their choices. You are there to guide them, provide information and offer suggestions. But it has to be a 2 way process, by helping them you will also develop your skills because â€Å"teaching is itself a learning process for the teacher† (Joyce, Showers 2002). Everyone is different and you need to be prepared and have contingency plans for all levels of knowledge and skill – you will find bored students make bad students. They don’t just have a variety of levels but also different learning styles, be sure to have a mix of kinaesthetic, visual and audio resources. You can use handouts with the camera instructions on, a video showing how it works, and then let them try themselves. It is your responsibility to ensure all students no matter how diverse are given equal learning opportunities – that means assuming different roles. So for Learner X (names are confidential) you need to be firm, authoritative, Learner Y asks a lot of questions – be prepared to listen and summarise, Learner Z needs more encouragement.

SCI Case Study

1. Why did Allen’s heart rate and blood pressure fall in this time of emergency (i.e. at a time when you’d expect just the opposite homeostatic response)? Pg. 969 This occurred because Allen’s spinal cord has decreased perfusion due to damage, and a broken vertebral bone. Also, there has been a disruptions of the sympathetic fibers of his autonomic nervous system therefore it can no longer stimulate the heart. Allen likely has spinal shock.2. Upon admission to the hospital, Allen’s breathing was rapid and shallow, can you explain why? Pg. 969 Due to Allen’s fall he likely has an incompetent diaphragm due to injuring a cervical segment. This would alter effect the lower motor neurons and external intercostal muscles. This would cause his chest x-ray to show a decreased lung expansion. This may have caused Allen to have to take rapid shallow breaths to maintain oxygenation. Overall, interruption of spinal innervation to the respiratory muscles would a lso explain his acidotic state.3. Why did Allen lose some sensation to his arms and all sensation from the upper trunk down? This is because Allen’s C5 segment was injured. Therefore, the dorsal column tracts and spinothalamic tracts were altered. This would cause Allen to have lost and decreased sensations.4. Why did Allen have dry skin and a fever upon admission to the hospital? pg. 970 The rationale for the dry skin and fever is that Allen had lack of sympathetic and hypothalamic control. Therefore, his body adapted to the temperature of the environment as wells as attempting to increase extracellular fluid. Overall, spinal shock would result in these symptoms along with decreased sweat production resulting from decreased sympathetic motor neuron stimulation.5. Based on the physical exam findings, which vertebral bone do you think was fractured? Give reasons for your answers? Pg. 969 Based on the physical findings I would say Allen’s fracture occurred at C5. I belie ve this is  where the fracture occurred because Allen had minimal biceps brachial stretch reflex, was able to raise his shoulders and tighten them, and could tighten his biceps.In addition Allen could not raise his arms against gravity, had flaccid lower extremities, and was without triceps or wrist extensor reflexes, and other muscle stretch reflexes were absent. If the fracture was at C4-5 Allen would not be able to shrug his shoulders and if the fracture was at C7 he could extend his flexed arms. Top of FormBottom of Form6. What is the normal pH of blood? Why was Allen’s blood pH below normal? Pg. 970-971. The normal blood pH is between 7.35 and 7.45. Allen’s blood was acidotic due to a decrease in lung expansion and an alteration in the perfusion to his spinal cord. He also has an alteration in spinal innervation to the respiratory muscles including the phrenic nerve that controls the diaphragm. This would further cause Allen to not be able to adequately take in enough oxygen and blow off enough CO2 to adequately have gas exchange, within the alveoli. Respiratory failure.7. What is the primary muscle of respiration? What nerve initiates this muscle? The primary muscle of respiration is the diaphragm. The nerve that initiates this muscle is the phrenic nerve.8. Which spinal neurons to the nerve you named in question #7? Pg. 969. The cervical spinal nerve C3-5 innervate the phrenic nerve. These are the lower motor neurons.9. By four days after the injury, some of Allen’s signs and symptoms had changed. Allen’s arm muscles were still flaccid, yet his leg muscles had become spastic and exhibited exaggerated stretch reflexes. Use your knowledge of motor neural pathways to explain these findings. Pg. 969. Allen is experiencing these signs and symptoms because he is his spinal shock is now resolved. Therefore his lower motor neurons will then be able to fire impulses unlike the upper motor neurons due to the injury being at C5. There fore, due to his cervical injury muscle spasticity, bladder activity, and reflex activity will begin. This is called spastic paralysis.10. Why did Allen suffer from urinary incontinence? Pg. 970. Allen suffered from urinary incontinence because of autonomic dysfunction. Initially autonomic dysfunction causes an areflexic bladder, also known as a neurogenic bladder. This means his bladder had zero ability to contract. Autonomic dysfunction then leads to urinary retention.

Security in the Workplace Essay Example | Topics and Well Written Essays - 6250 words

Security in the Workplace - Essay Example The term security may include integrated security, physical security, company security, hiring issues, etc. Some situations may be emergencies, which definitely require a proactive procedure. Emergencies should be prevented as much as possible and that is why it is important to determine what might be an emergency, or what might lead to an emergency. If an emergency or a safety need does arise, it is detrimental that systems and policies are in place. This will not only avoid confusion and lack of readiness and education, it will minimize injuries, accidents, and liabilities. When safety/securities needs are overlooked, they can cause problems for everyone and this causes lawsuits and liabilities. The organization, with the security manager’s guidance, should look out for the safety and security of all those who enter and have dealings with the company. The security manager should also help provide a secured environment by teaching administration/management and staff how to ab ide the systems and policies, focusing on intrusion prevention and detection, consistent auditing, and computer security. Management is the authority in which the staff follows and they also provide the standard for any visitors and clients who deal with the organization, or company. Management should know what to look for during the hiring process to prevent future problems. Security in the Workplace 2 Nixon states, "Poor hiring practices can cost a company in lost productivity, theft, and at the extreme end, workplace violence incidents that can cost lives, damage the company's reputation, and depress future earnings. Legal expenses for negligence lawsuits (for issues including negligent hiring, supervision, security, training, and retention) average $2.2 million, according to Rebecca Speer, a workplace-violence attorney. But more devastating is the loss of life that violence in the workplace can cause. To minimize the risk of such incidents, companies need to implement a well-crafted hiring process that screens out violence- prone candidates before they become employees". Steps in the hiring process will lead to risk management, a safer environment for all, and fewer liabilities. "One of the simplest self-opt-out techniques is to declare the organization a "violence-free workplace," just as some organizations proclaim that they are a drug-free workplace and therefore test all applicants for drugs. If, from the outset of the hiring process, a company makes clear that its selection process focuses on individuals who will support efforts to keep the environment free of violence, individuals who have been used to displaying aggressive, hostile, and violent behavior will go elsewhere or will join the company with the understanding that this behavior is not acceptable," states Nixon. Screening candidates during job interviews is an excellent way to insure a safe and secure environment. Be sure to choose questions that are helpful in meeting your Security in the Workplace 3 organization's goals, do background checks, investigate inconsistent work history, and contact each candidate's references. Be sure to have job candidates sign a form which states that, should he/she be hired, listing false information on an application is reason for termination. The theoretical foundation for security is to determine every possible issue and concern regarding safety and security in order to plan, develop, implement, enforce,

Autism Essay Example | Topics and Well Written Essays - 500 words

Autism - Essay Example st provided by the DSM-IV is quite comprehensive since the primary symptoms include qualitative difficulty in social interaction shown by things like impairments in the use of nonverbal behavior. This is particularly true if the child attempts their simultaneous use, a failure to develop relationships with peers, a lack of interest in different objects and a failure to show emotional reciprocity (Autistics, 2002). Additionally, a person with autism may show qualitative impairments in developing language skills, difficulties in maintaining conversations, idiosyncratic language and a lack of make believe play (Wikipedia, 2006). There are also minor criteria listed in the DSM-IV but the major symptoms are far more important for a diagnosis of autism which needs a physiological and neurological evaluation (Autistics, 2002). As a disorder, autism may present it self in a wide variety of ways, since people with autism may be nearly dysfunctional and appear to be mentally disabled to those whose symptoms are mild or remedied enough to appear normal to others (Wikipedia, 2006). Even though the actual causes of autism are not known, there has been some evidence found which links genetics to autism. Researchers at the University of Pennsylvania have also linked autism to abnormal blood vessel function and oxidative stress. The majority of individuals with autism also have increased brain size but the link between the two is not clearly established as of yet. As the understanding of the causes of the disorder is improved with time, the methods of treatment and diagnosis should also improve (Wikipedia, 2006). The methods of treatment and handling of the disorder depend on early detection and intervention. The mitigation of the disorder requires intensive therapies such as applied behavioral analysis, parental and caregiver training, practice with the individual, and in many cases, special schooling. It must be noted that a complete cure of autism is often impossible since

Individual assignment Essay Example | Topics and Well Written Essays - 750 words

Individual assignment - Essay Example Bhide concurs with this position by stating that financial services firms must prove themselves every day – in terms of profits and competitive advantage – because a strategy might be successful today and ineffective tomorrow. Bhide rubbishes the traditional, subjective concept for this sector by demonstrating that as a result of the volatile nature of financial products and services, they can be copied quickly. He suggests that there is no consistent flow of new opportunities available, so firms should concentrate on doing all they can to reduce their chances of failure. The author suggests that strategy should resemble poker rather than chess, where firms concentrate on strategy and execution instead of putting up massive barriers to rivals. The author cites Warren Buffet, who said that core sustainable competitive advantages are virtually non-existent in the financial services sector (Chermack, 2011:35). Financial services firms have no monopoly on excellent product ideas, so they must secure clients by implanting ideas better than their rivals (Gong, 2013:15). In spite of this, other scholars disagree by arguing that possessing operational efficiency or effectiveness is insufficient for companies and that these strategies lead to some firms outlasting others but offering no real competitive advantage in the industry (Gong, 2013:15). Bhide acknowledges that financial services firms must develop and enforce appraisal systems to avoid irresponsibility. He argues that financial services firms should evaluate their performance and constantly analyse current and potential risks. This idea has been proposed by other scholars, who have argued that firms with novel strategies should have sufficient structures to support the emergence of patterns, but not so much that it increases cost and triggers inflexibility (Hitt and Ireland, 2013:45). It can be argued that novel strategies are not about the lack of authority;